OPG Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: OPG Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-20624R-BIOTIN-TRIAL
• Supplier Catalog Number: bs-20624R-Biotin
• Alternative Catalog Number: BSS-BS-20624R-BIOTIN-20
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Biotin
• Alternative Names: Tumor necrosis factor receptor superfamily member 11B, TNFRSF11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, OCIF, OPG

Product Description

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 367
• UniProt: O00300
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human OPG
• Purity: Purified by Protein A.
• Target: OPG
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)