phospho-FANCD2 (Ser222) Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: phospho-FANCD2 (Ser222) Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BS-3015R
• Hersteller Artikelnummer: bs-3015R
• Alternativnummer: BSS-BS-3015R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: FANCD2 phospho S222, FANCD2 phospho Ser222, p-FANCD2 phospho S222, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

Produktbeschreibung

Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 2177
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222
• Target-Kategorie: phospho-FANCD2 (Ser222)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)