phospho-FANCD2 (Ser222) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: phospho-FANCD2 (Ser222) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3015R
• Supplier Catalog Number: bs-3015R
• Alternative Catalog Number: BSS-BS-3015R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: FANCD2 phospho S222, FANCD2 phospho Ser222, p-FANCD2 phospho S222, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

Product Description

Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2177
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222
• Target: phospho-FANCD2 (Ser222)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)