Phospho-FoxO3a (Ser253) Polyclonal Antibody, PE Conjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-FoxO3a (Ser253) Polyclonal Antibody, PE Conjugated, Rabbit
• Artikelnummer: BSS-BS-3140R-PE
• Hersteller Artikelnummer: bs-3140R-PE
• Alternativnummer: BSS-BS-3140R-PE-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IF, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: PE
• Alternative Synonym: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3

Produktbeschreibung

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5-[AG]TAAA[TC]A-3. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3UTR of MYC transcript and prevent its translation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 2309
• UniProt: O43524
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253
• Target-Kategorie: Phospho-FoxO3a (Ser253)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)