Phospho-FoxO3a (Ser253) Polyclonal Antibody, PE Conjugated, Rabbit

Product Overview

• Article Name: Phospho-FoxO3a (Ser253) Polyclonal Antibody, PE Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-3140R-PE
• Supplier Catalog Number: bs-3140R-PE
• Alternative Catalog Number: BSS-BS-3140R-PE-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE
• Alternative Names: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3

Product Description

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5-[AG]TAAA[TC]A-3. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3UTR of MYC transcript and prevent its translation.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2309
• UniProt: O43524
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253
• Target: Phospho-FoxO3a (Ser253)

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)