Recombinant human ADAMTS5 protein, Unconjugated

Produktübersicht

• Artikelname: Recombinant human ADAMTS5 protein, Unconjugated
• Artikelnummer: BSS-BS-42150P
• Hersteller Artikelnummer: bs-42150P
• Alternativnummer: BSS-BS-42150P-100,BSS-BS-42150P-500
• Hersteller: Bioss
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Other
• Konjugation: Unconjugated

Produktbeschreibung

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]

Produkteigenschaften

• Tag: N-His
• NCBI: 23794
• UniProt: Q9UNA0
• Puffer: 20mM Tris (pH8.0) with 8M Urea.
• Quelle: Recombinant human ADAMTS5 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 739-930/930
• Expression System: E.coli
• Reinheit: > 90% as determined by SDS- PAGE