Recombinant human ADAMTS5 protein, Unconjugated

Product Overview

• Article Name: Recombinant human ADAMTS5 protein, Unconjugated
• Biozol Catalog Number: BSS-BS-42150P
• Supplier Catalog Number: bs-42150P
• Alternative Catalog Number: BSS-BS-42150P-100,BSS-BS-42150P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]

Product Properties

• Tag: N-His
• NCBI: 23794
• UniProt: Q9UNA0
• Buffer: 20mM Tris (pH8.0) with 8M Urea.
• Source: Recombinant human ADAMTS5 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 739-930/930
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE