UNC0642 --- G9a/GLP HMTase Inhibitor, CAS [[1481677-78-4]], Unconjugated

Produktübersicht

• Artikelname: UNC0642 --- G9a/GLP HMTase Inhibitor, CAS [[1481677-78-4]], Unconjugated
• Artikelnummer: BSS-BS-60185C
• Hersteller Artikelnummer: bs-60185C
• Alternativnummer: BSS-BS-60185C-10,BSS-BS-60185C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

UNC0642 is a novel highly potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with IC50 < 2.5 nM. It has selectivity > 1000-fold over 13 other HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. UNC0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50~110 nM). It has improved PK properties relative to UNC0638 and displayed modest brain penetration in vivo.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [1481677-78-4]