Bub3 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Bub3 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-7835R-BIOTIN
• Hersteller Artikelnummer: bs-7835R-Biotin
• Alternativnummer: BSS-BS-7835R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Rat
• Konjugation: Biotin
• Alternative Synonym: BUB3L, hBUB3, Mitotic checkpoint protein BUB3, BUB3

Produktbeschreibung

Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 9184
• UniProt: O43684
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Bub3
• Target-Kategorie: Bub3

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)