XRCC4 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: XRCC4 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-8510R-BIOTIN
• Hersteller Artikelnummer: bs-8510R-Biotin
• Alternativnummer: BSS-BS-8510R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4

Produktbeschreibung

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 7518
• UniProt: Q13426
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human XRCC4
• Target-Kategorie: XRCC4

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)