XRCC4 Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: XRCC4 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-8510R-BIOTIN
• Supplier Catalog Number: bs-8510R-Biotin
• Alternative Catalog Number: BSS-BS-8510R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4

Product Description

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 7518
• UniProt: Q13426
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human XRCC4
• Target: XRCC4

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)