Bcl-2 Monoclonal Antibody, PE Conjugated, Clone: [1A5], Mouse
Artikelnummer:
BSS-BSM-10846M-PE
Hersteller Artikelnummer:
bsm-10846M-PE
Alternativnummer:
BSS-BSM-10846M-PE-100
Hersteller:
Bioss
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Konjugation:
PE
Alternative Synonym:
Apoptosis regulator Bcl-2, BCL2
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
