Bcl-2 Monoclonal Antibody, PE Conjugated, Clone: [1A5], Mouse
Biozol Catalog Number:
BSS-BSM-10846M-PE
Supplier Catalog Number:
bsm-10846M-PE
Alternative Catalog Number:
BSS-BSM-10846M-PE-100
Manufacturer:
Bioss
Host:
Mouse
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
Apoptosis regulator Bcl-2, BCL2
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release
