CD45 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [14A9], Mouse

Produktübersicht

• Artikelname: CD45 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [14A9], Mouse
• Artikelnummer: BSS-BSM-33052M-BIOTIN
• Hersteller Artikelnummer: bsm-33052M-Biotin
• Alternativnummer: BSS-BSM-33052M-BIOTIN-100
• Hersteller: Bioss
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: B220, CD 45, CD-45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Ly-5 glycoprotein, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.

Produktbeschreibung

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 1ug/ul
• Klon-Bezeichnung: [14A9]
• Isotyp: IgG1
• NCBI: 5788
• UniProt: P08575
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: Recombinant human CD45
• Target-Kategorie: CD45

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)