CD45 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [14A9], Mouse

Product Overview

• Article Name: CD45 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [14A9], Mouse
• Biozol Catalog Number: BSS-BSM-33052M-BIOTIN
• Supplier Catalog Number: bsm-33052M-Biotin
• Alternative Catalog Number: BSS-BSM-33052M-BIOTIN-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: B220, CD 45, CD-45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Ly-5 glycoprotein, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.

Product Description

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [14A9]
• Isotype: IgG1
• NCBI: 5788
• UniProt: P08575
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Recombinant human CD45
• Target: CD45

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)