DNA Ligase IV Recombinant Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: DNA Ligase IV Recombinant Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BSM-54131R
• Hersteller Artikelnummer: bsm-54131R
• Alternativnummer: BSS-BSM-54131R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.

Produktbeschreibung

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: 1ug/ul
• NCBI: 3981
• UniProt: P49917
• Puffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Quelle: Recombinant protein within human DNA Ligase IV aa 500-700
• Target-Kategorie: LIG4

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), ICC/IF(1:50-100)