DNA Ligase IV Recombinant Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: DNA Ligase IV Recombinant Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-54131R
• Supplier Catalog Number: bsm-54131R
• Alternative Catalog Number: BSS-BSM-54131R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.

Product Description

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Product Properties

• Clonality: Recombinant
• Concentration: 1ug/ul
• NCBI: 3981
• UniProt: P49917
• Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Source: Recombinant protein within human DNA Ligase IV aa 500-700
• Target: LIG4

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), ICC/IF(1:50-100)