Granzyme B Monoclonal Antibody, Biotin Conjugated, Clone: [H12A5], Rabbit

Artikelnummer: BSS-BSM-60779R-BIOTIN
Artikelname: Granzyme B Monoclonal Antibody, Biotin Conjugated, Clone: [H12A5], Rabbit
Artikelnummer: BSS-BSM-60779R-BIOTIN
Hersteller Artikelnummer: bsm-60779R-Biotin
Alternativnummer: BSS-BSM-60779R-BIOTIN-100
Hersteller: Bioss
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC-Fr, IHC-P, WB
Spezies Reaktivität: Human
Konjugation: Biotin
Alternative Synonym: GranzymeB, Granzyme-B, C11, Cathepsin G-like 1, CTLA-1, Cathespin G Like 1, CCPI, CCP-1, CGL 1, CGL1, CSP B, CSPB, CTLA 1,CTLA1, CTSGL 1, CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Associated Serine Esterase 1, Cytotoxic T lymphocyte proteinase 2, Fragmentin 2, Fragmentin2, Granzyme 2, Granzyme2, GRB, GZMB, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRAB_HUMAN, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1), Granzyme B, Granzyme-2, GranzymeB, HLP, T cell serine protease 1 3E, T cell serine protease 1-3E, T-cell serine protease 1-3E, HLP, Human lymphocyte protein, Lymphocyte protease, Protease Serine B, SECT, AA 18-29, T cell serine protease 1.
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Klonalität: Monoclonal
Konzentration: Lot dependent
Klon-Bezeichnung: [H12A5]
NCBI: 3002
UniProt: P10144
Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle: KLH conjugated synthetic peptide derived from human GZMB
Reinheit: Purified by Protein A.
Target-Kategorie: Granzyme B
Antibody Type: Primary Antibody
Application Verdünnung: WB(WB(1:500-2000)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200))