Granzyme B Monoclonal Antibody, Biotin Conjugated, Clone: [H12A5], Rabbit
Catalog Number:
BSS-BSM-60779R-BIOTIN
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| Article Name: | Granzyme B Monoclonal Antibody, Biotin Conjugated, Clone: [H12A5], Rabbit |
| Biozol Catalog Number: | BSS-BSM-60779R-BIOTIN |
| Supplier Catalog Number: | bsm-60779R-Biotin |
| Alternative Catalog Number: | BSS-BSM-60779R-BIOTIN-100 |
| Manufacturer: | Bioss |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IHC-Fr, IHC-P, WB |
| Species Reactivity: | Human |
| Conjugation: | Biotin |
| Alternative Names: | GranzymeB, Granzyme-B, C11, Cathepsin G-like 1, CTLA-1, Cathespin G Like 1, CCPI, CCP-1, CGL 1, CGL1, CSP B, CSPB, CTLA 1,CTLA1, CTSGL 1, CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Associated Serine Esterase 1, Cytotoxic T lymphocyte proteinase 2, Fragmentin 2, Fragmentin2, Granzyme 2, Granzyme2, GRB, GZMB, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRAB_HUMAN, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1), Granzyme B, Granzyme-2, GranzymeB, HLP, T cell serine protease 1 3E, T cell serine protease 1-3E, T-cell serine protease 1-3E, HLP, Human lymphocyte protein, Lymphocyte protease, Protease Serine B, SECT, AA 18-29, T cell serine protease 1. |
| This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| Clonality: | Monoclonal |
| Concentration: | Lot dependent |
| Clone Designation: | [H12A5] |
| NCBI: | 3002 |
| UniProt: | P10144 |
| Buffer: | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Source: | KLH conjugated synthetic peptide derived from human GZMB |
| Purity: | Purified by Protein A. |
| Target: | Granzyme B |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB(WB(1:500-2000)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)) |
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