TLR4 Monoclonal Antibody, IgG1, Clone: [1G12], Unconjugated, Mouse

Artikelnummer: BSS-BSM-60911M
Artikelname: TLR4 Monoclonal Antibody, IgG1, Clone: [1G12], Unconjugated, Mouse
Artikelnummer: BSS-BSM-60911M
Hersteller Artikelnummer: bsm-60911M
Alternativnummer: BSS-BSM-60911M-100
Hersteller: Bioss
Wirt: Mouse
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Mouse
Konjugation: Unconjugated
Alternative Synonym: TLR-4, TLR 4, ARMD10, CD 284, CD284, CD284 antigen, Homolog of Drosophila toll, hTol, Toll (Drosophila) homolog, TOLL, Toll Endotoxin Hyporesponsiveness, Toll like receptor 4, Toll like receptor 4 precursor, TLR4_HUMAN.
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.
Klonalität: Monoclonal
Konzentration: 1ug/ul
Klon-Bezeichnung: [1G12]
Isotyp: IgG1
NCBI: 7099
UniProt: O00206
Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle: KLH conjugated synthetic peptide derived from human TLR4
Reinheit: Purified by Protein G.
Target-Kategorie: TLR4
Antibody Type: Primary Antibody
Application Verdünnung: WB(WB(1:500-2000))