TLR4 Monoclonal Antibody, IgG1, Clone: [1G12], Unconjugated, Mouse

Product Overview

• Article Name: TLR4 Monoclonal Antibody, IgG1, Clone: [1G12], Unconjugated, Mouse
• Biozol Catalog Number: BSS-BSM-60911M
• Supplier Catalog Number: bsm-60911M
• Alternative Catalog Number: BSS-BSM-60911M-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Mouse
• Conjugation: Unconjugated
• Alternative Names: TLR-4, TLR 4, ARMD10, CD 284, CD284, CD284 antigen, Homolog of Drosophila toll, hTol, Toll (Drosophila) homolog, TOLL, Toll Endotoxin Hyporesponsiveness, Toll like receptor 4, Toll like receptor 4 precursor, TLR4_HUMAN.

Product Description

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [1G12]
• Isotype: IgG1
• NCBI: 7099
• UniProt: O00206
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human TLR4
• Purity: Purified by Protein G.
• Target: TLR4
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(WB(1:500-2000))