Caspase-3 Recombinant Antibody, APC Conjugated, Rabbit

Produktübersicht

• Artikelname: Caspase-3 Recombinant Antibody, APC Conjugated, Rabbit
• Artikelnummer: BSS-BSM-61071R-APC
• Hersteller Artikelnummer: bsm-61071R-APC
• Alternativnummer: BSS-BSM-61071R-APC-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: APC
• Alternative Synonym: cleaved Caspase 3, cleaved Caspase-3, APOPAIN, CASP3, Caspase 3 apoptosis related cysteine protease, Caspase3, CPP32, CPP32B, Cysteine protease CPP32, Human cysteine protease CPP32 isoform alpha mRNA complete cds, PARP cleavage protease, SCA 1, SCA1, SREBP cleavage activity 1, Yama, CASP3_HUMAN, Caspase-3, CASP-3, Apopain, Protein Yama, SREBP cleavage activity 1, SCA-1.

Produktbeschreibung

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 836
• UniProt: P42574
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Caspase-3
• Reinheit: Purified by Protein A.
• Target-Kategorie: Caspase-3
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB(WB(1:1000-5000)), IF(IHC-P)(IF(IHC-P)(1:200-800))