Caspase-3 Recombinant Antibody, APC Conjugated, Rabbit

Product Overview

• Article Name: Caspase-3 Recombinant Antibody, APC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-61071R-APC
• Supplier Catalog Number: bsm-61071R-APC
• Alternative Catalog Number: BSS-BSM-61071R-APC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: APC
• Alternative Names: cleaved Caspase 3, cleaved Caspase-3, APOPAIN, CASP3, Caspase 3 apoptosis related cysteine protease, Caspase3, CPP32, CPP32B, Cysteine protease CPP32, Human cysteine protease CPP32 isoform alpha mRNA complete cds, PARP cleavage protease, SCA 1, SCA1, SREBP cleavage activity 1, Yama, CASP3_HUMAN, Caspase-3, CASP-3, Apopain, Protein Yama, SREBP cleavage activity 1, SCA-1.

Product Description

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 836
• UniProt: P42574
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human Caspase-3
• Purity: Purified by Protein A.
• Target: Caspase-3
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(WB(1:1000-5000)), IF(IHC-P)(IF(IHC-P)(1:200-800))