ULK3 Recombinant Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: ULK3 Recombinant Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BSM-61618R
• Hersteller Artikelnummer: bsm-61618R
• Alternativnummer: BSS-BSM-61618R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: Serine/threonine-protein kinase ULK3, Ulk3, unc 51 like kinase 3 (C. elegans), Unc-51-like kinase 3.

Produktbeschreibung

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 25989
• UniProt: Q6PHR2
• Puffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Quelle: KLH conjugated synthetic peptide derived from human ULK3
• Target-Kategorie: ULK3

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), FCM(1ug/Test), ICC/IF(1:50-100)