ULK3 Recombinant Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: ULK3 Recombinant Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-61618R
• Supplier Catalog Number: bsm-61618R
• Alternative Catalog Number: BSS-BSM-61618R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Serine/threonine-protein kinase ULK3, Ulk3, unc 51 like kinase 3 (C. elegans), Unc-51-like kinase 3.

Product Description

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 25989
• UniProt: Q6PHR2
• Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Source: KLH conjugated synthetic peptide derived from human ULK3
• Target: ULK3

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), FCM(1ug/Test), ICC/IF(1:50-100)