Phospho-CRK (Tyr221) Recombinant Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-CRK (Tyr221) Recombinant Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BSM-61622R
• Hersteller Artikelnummer: bsm-61622R
• Alternativnummer: BSS-BSM-61622R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IF, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk.

Produktbeschreibung

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 1398
• UniProt: P46108
• Puffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Quelle: KLH conjugated synthetic peptide derived from human CRK around the phosphorylation site of Y221
• Target-Kategorie: CRK (Tyr221)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ICC/IF(1:50-100)