Phospho-CRK (Tyr221) Recombinant Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-CRK (Tyr221) Recombinant Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-61622R
• Supplier Catalog Number: bsm-61622R
• Alternative Catalog Number: BSS-BSM-61622R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IF, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk.

Product Description

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 1398
• UniProt: P46108
• Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Source: KLH conjugated synthetic peptide derived from human CRK around the phosphorylation site of Y221
• Target: CRK (Tyr221)

Application Notes

• Application Dilute: WB(1:300-5000), ICC/IF(1:50-100)