Human PR3 Ready-To-Use IHC Kit

Produktübersicht

• Artikelname: Human PR3 Ready-To-Use IHC Kit
• Artikelnummer: BSS-IHC0393H
• Hersteller Artikelnummer: IHC0393H
• Alternativnummer: BSS-IHC0393H-50
• Hersteller: Bioss
• Kategorie: Kits/Assays
• Spezies Reaktivität: Human
• Alternative Synonym: ACPA, C-ANCA, CANCA, MBT, NP4, Myeloblastin, AGP7, C-ANCA Antigen, Leukocyte Proteinase 3, PR-3, PR3, Neutrophil Proteinase 4, NP-4, P29, Wegener Autoantigen, PRTN3, MBNa

Produktbeschreibung

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelialmigration, probably when associated with CD177 (PubMed:22266279).

Produkteigenschaften

• Proben: FFPE tissue
• Target-Kategorie: Human PR3

Bilder

IHC0393H