Human PR3 Ready-To-Use IHC Kit

Product Overview

• Article Name: Human PR3 Ready-To-Use IHC Kit
• Biozol Catalog Number: BSS-IHC0393H
• Supplier Catalog Number: IHC0393H
• Alternative Catalog Number: BSS-IHC0393H-50
• Manufacturer: Bioss
• Category: Kits/Assays
• Species Reactivity: Human
• Alternative Names: ACPA, C-ANCA, CANCA, MBT, NP4, Myeloblastin, AGP7, C-ANCA Antigen, Leukocyte Proteinase 3, PR-3, PR3, Neutrophil Proteinase 4, NP-4, P29, Wegener Autoantigen, PRTN3, MBNa

Product Description

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelialmigration, probably when associated with CD177 (PubMed:22266279).

Product Properties

• Samples: FFPE tissue
• Target: Human PR3

Images

IHC0393H