Cathepsin D (K345) polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS3673
Artikelname: Cathepsin D (K345) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS3673
Hersteller Artikelnummer: BS3673
Alternativnummer: BWT-BS3673-50UL,BWT-BS3673-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 311-360 of Human Cathepsin D.
Konjugation: Unconjugated
Alternative Synonym: Cathepsin D, CTSD, CPSD
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
Molekulargewicht: ~ 45 kDa
UniProt: P07339
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: IHC: 1:50~1:200
Anwendungsbeschreibung: Cathepsin D (K345) polyclonal antibody detects endogenous levels of Cathepsin D protein.