Cathepsin D (K345) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS3673
Supplier Catalog Number:
BS3673
Alternative Catalog Number:
BWT-BS3673-50UL,BWT-BS3673-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide, corresponding to amino acids 311-360 of Human Cathepsin D.
Conjugation:
Unconjugated
Alternative Names:
Cathepsin D, CTSD, CPSD
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
IHC: 1:50~1:200
Application Notes:
Cathepsin D (K345) polyclonal antibody detects endogenous levels of Cathepsin D protein.
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