PI 3 kinase p110 alpha Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: PI 3 kinase p110 alpha Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS40084
• Hersteller Artikelnummer: BS40084
• Alternativnummer: BWT-BS40084-50UL,BWT-BS40084-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha
• Konjugation: Unconjugated
• Alternative Synonym: PI 3 Kinase catalytic subunit alpha, phosphoinositide-3-kinase catalytic alpha polypeptide, PI3-kinase p110 alpha, PI3K, PI3K p110-alpha, PK3CA, PIK3CA, PtdIns-3-kinase p110

Produktbeschreibung

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Produkteigenschaften

• Molekulargewicht: 110kDa
• UniProt: P42336
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:20
• Anwendungsbeschreibung: PI 3 Kinase catalytic subunit alpha detects endogenous levels of total PI 3 Kinase catalytic subunit alpha