PI 3 kinase p110 alpha Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: PI 3 kinase p110 alpha Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40084
• Supplier Catalog Number: BS40084
• Alternative Catalog Number: BWT-BS40084-50UL,BWT-BS40084-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha
• Conjugation: Unconjugated
• Alternative Names: PI 3 Kinase catalytic subunit alpha, phosphoinositide-3-kinase catalytic alpha polypeptide, PI3-kinase p110 alpha, PI3K, PI3K p110-alpha, PK3CA, PIK3CA, PtdIns-3-kinase p110

Product Description

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Product Properties

• Molecular Weight: 110kDa
• UniProt: P42336
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:20
• Application Notes: PI 3 Kinase catalytic subunit alpha detects endogenous levels of total PI 3 Kinase catalytic subunit alpha