LGR5/GPR49 Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: LGR5/GPR49 Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS40123
• Hersteller Artikelnummer: BS40123
• Alternativnummer: BWT-BS40123-50UL,BWT-BS40123-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human LGR5/GPR49
• Konjugation: Unconjugated
• Alternative Synonym: FEX, GPR49, GPR67, GRP49, LGR5, HG38,8

Produktbeschreibung

Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Produkteigenschaften

• Molekulargewicht: 100kDa
• UniProt: O75473
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500~1:2000 IP 1:50 FC 1:200
• Anwendungsbeschreibung: LGR5/GPR49 Antibody detects endogenous levels of total LGR5/GPR49