LGR5/GPR49 Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: LGR5/GPR49 Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40123
• Supplier Catalog Number: BS40123
• Alternative Catalog Number: BWT-BS40123-50UL,BWT-BS40123-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: FC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human LGR5/GPR49
• Conjugation: Unconjugated
• Alternative Names: FEX, GPR49, GPR67, GRP49, LGR5, HG38,8

Product Description

Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Product Properties

• Molecular Weight: 100kDa
• UniProt: O75473
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:2000 IP 1:50 FC 1:200
• Application Notes: LGR5/GPR49 Antibody detects endogenous levels of total LGR5/GPR49