c-Maf Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: c-Maf Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS40162
• Hersteller Artikelnummer: BS40162
• Alternativnummer: BWT-BS40162-50UL,BWT-BS40162-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human c-Maf
• Konjugation: Unconjugated
• Alternative Synonym: Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene, c-MAF, c-maf proto-oncogene, cMaf, MAF, MGC71685, Proto-oncogene c-Maf,

Produktbeschreibung

Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

Produkteigenschaften

• Molekulargewicht: kDa
• UniProt: O75444
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: IHC 1:50~1:200
• Anwendungsbeschreibung: c-Maf Antibody detects endogenous levels of total c-Maf