c-Maf Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: c-Maf Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40162
• Supplier Catalog Number: BS40162
• Alternative Catalog Number: BWT-BS40162-50UL,BWT-BS40162-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human c-Maf
• Conjugation: Unconjugated
• Alternative Names: Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene, c-MAF, c-maf proto-oncogene, cMaf, MAF, MGC71685, Proto-oncogene c-Maf,

Product Description

Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

Product Properties

• Molecular Weight: kDa
• UniProt: O75444
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: IHC 1:50~1:200
• Application Notes: c-Maf Antibody detects endogenous levels of total c-Maf