MEK7 Rabbit monoclonal antibody, Unconjugated

Artikelnummer: BWT-BS40307
Artikelname: MEK7 Rabbit monoclonal antibody, Unconjugated
Artikelnummer: BWT-BS40307
Hersteller Artikelnummer: BS40307
Alternativnummer: BWT-BS40307-50UL,BWT-BS40307-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IHC, IP, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human MEK7
Konjugation: Unconjugated
Alternative Synonym: MKK7, Jnkk2, MAPKK7, PRKMK7, JNK-activating kinase 2, MAPKK 7, Mitogen Activated Protein Kinase kinase 7, SAPKK4, stress-activated protein kinase kinase 4,
MKK7 is strongly activated by TNF-alpha, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-alpha. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.
Molekulargewicht: 47kDa
UniProt: O14733
Reinheit: Affinity-chromatography
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Verdünnung: WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:50
Anwendungsbeschreibung: MEK7 Antibody detects endogenous levels of MEK7