MEK7 Rabbit monoclonal antibody, Unconjugated

Catalog Number: BWT-BS40307
Article Name: MEK7 Rabbit monoclonal antibody, Unconjugated
Biozol Catalog Number: BWT-BS40307
Supplier Catalog Number: BS40307
Alternative Catalog Number: BWT-BS40307-50UL,BWT-BS40307-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: FC, ICC, IHC, IP, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human MEK7
Conjugation: Unconjugated
Alternative Names: MKK7, Jnkk2, MAPKK7, PRKMK7, JNK-activating kinase 2, MAPKK 7, Mitogen Activated Protein Kinase kinase 7, SAPKK4, stress-activated protein kinase kinase 4,
MKK7 is strongly activated by TNF-alpha, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-alpha. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.
Molecular Weight: 47kDa
UniProt: O14733
Purity: Affinity-chromatography
Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Dilute: WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:50
Application Notes: MEK7 Antibody detects endogenous levels of MEK7