Granzyme B Rabbit monoclonal antibody, Unconjugated
Artikelnummer:
BWT-BS40492
Produktübersicht
Artikelname:
Granzyme B Rabbit monoclonal antibody, Unconjugated
Artikelnummer:
BWT-BS40492
Hersteller Artikelnummer:
BS40492
Alternativnummer:
BWT-BS40492-50UL,BWT-BS40492-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ICC, IHC, IP
Spezies Reaktivität:
Human
Immunogen:
A synthesized peptide derived from human Granzyme B
Konjugation:
Unconjugated
Alternative Synonym:
Granzyme B, Cathepsin G-like 1, CTSGL1, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, SECT, GZMB, CGL1, CSPB, CTLA1, GRB,
Produktbeschreibung
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Produkteigenschaften
Molekulargewicht:
38kDa
UniProt:
P10144
Reinheit:
Affinity-chromatography
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Anwendungsbeschreibung
Application Verdünnung:
IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Anwendungsbeschreibung:
Granzyme B Antibody detects endogenous levels of total Granzyme B