Granzyme B Rabbit monoclonal antibody, Unconjugated

Artikelnummer: BWT-BS40492
Artikelname: Granzyme B Rabbit monoclonal antibody, Unconjugated
Artikelnummer: BWT-BS40492
Hersteller Artikelnummer: BS40492
Alternativnummer: BWT-BS40492-50UL,BWT-BS40492-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ICC, IHC, IP
Spezies Reaktivität: Human
Immunogen: A synthesized peptide derived from human Granzyme B
Konjugation: Unconjugated
Alternative Synonym: Granzyme B, Cathepsin G-like 1, CTSGL1, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, SECT, GZMB, CGL1, CSPB, CTLA1, GRB,
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Molekulargewicht: 38kDa
UniProt: P10144
Reinheit: Affinity-chromatography
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Verdünnung: IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Anwendungsbeschreibung: Granzyme B Antibody detects endogenous levels of total Granzyme B