Granzyme B Rabbit monoclonal antibody, Unconjugated
Catalog Number:
BWT-BS40492
Product Overview
Article Name:
Granzyme B Rabbit monoclonal antibody, Unconjugated
Biozol Catalog Number:
BWT-BS40492
Supplier Catalog Number:
BS40492
Alternative Catalog Number:
BWT-BS40492-50UL,BWT-BS40492-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
ICC, IHC, IP
Species Reactivity:
Human
Immunogen:
A synthesized peptide derived from human Granzyme B
Conjugation:
Unconjugated
Alternative Names:
Granzyme B, Cathepsin G-like 1, CTSGL1, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, SECT, GZMB, CGL1, CSPB, CTLA1, GRB,
Product Description
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Product Properties
Molecular Weight:
38kDa
UniProt:
P10144
Purity:
Affinity-chromatography
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Notes
Application Dilute:
IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Application Notes:
Granzyme B Antibody detects endogenous levels of total Granzyme B
