PHD2 / prolyl hydroxylase Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: PHD2 / prolyl hydroxylase Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS40613
• Hersteller Artikelnummer: BS40613
• Alternativnummer: BWT-BS40613-50UL,BWT-BS40613-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IP, WB
• Spezies Reaktivität: Human
• Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase
• Konjugation: Unconjugated
• Alternative Synonym: EGLN1, C1orf12, ECYT3, HIFPH2, HPH2, PHD2, SM-20, SM20, ZMYND6,

Produktbeschreibung

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Produkteigenschaften

• Molekulargewicht: 46kDa
• UniProt: Q9GZT9
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500~1:2000 IP 1:50
• Anwendungsbeschreibung: PHD2 / prolyl hydroxylase Antibody detects endogenous levels of total PHD2 / prolyl hydroxylase