PHD2 / prolyl hydroxylase Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: PHD2 / prolyl hydroxylase Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS40613
• Supplier Catalog Number: BS40613
• Alternative Catalog Number: BWT-BS40613-50UL,BWT-BS40613-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IP, WB
• Species Reactivity: Human
• Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase
• Conjugation: Unconjugated
• Alternative Names: EGLN1, C1orf12, ECYT3, HIFPH2, HPH2, PHD2, SM-20, SM20, ZMYND6,

Product Description

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Product Properties

• Molecular Weight: 46kDa
• UniProt: Q9GZT9
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:2000 IP 1:50
• Application Notes: PHD2 / prolyl hydroxylase Antibody detects endogenous levels of total PHD2 / prolyl hydroxylase