Hamartin Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: Hamartin Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS41107
• Hersteller Artikelnummer: BS41107
• Alternativnummer: BWT-BS41107-50UL,BWT-BS41107-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: A synthesized peptide derived from human Hamartin
• Konjugation: Unconjugated
• Alternative Synonym: Hamartin, kiaa0243, LAM, TSC, Tsc1, Tuberous sclerosis 1,

Produktbeschreibung

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Produkteigenschaften

• Molekulargewicht: 150kDa
• UniProt: Q92574
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:200
• Anwendungsbeschreibung: Hamartin Antibody detects endogenous levels of total Hamartin