PAG Rabbit monoclonal antibody, Unconjugated

Produktübersicht

• Artikelname: PAG Rabbit monoclonal antibody, Unconjugated
• Artikelnummer: BWT-BS41309
• Hersteller Artikelnummer: BS41309
• Alternativnummer: BWT-BS41309-50UL,BWT-BS41309-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IHC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human PAG
• Konjugation: Unconjugated
• Alternative Synonym: CBP, Csk binding protein, PAG, PAG1,

Produktbeschreibung

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.

Produkteigenschaften

• Molekulargewicht: 80kDa
• UniProt: Q9NWQ8
• Reinheit: Affinity-chromatography
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:100
• Anwendungsbeschreibung: PAG Antibody detects endogenous levels of total PAG