PAG Rabbit monoclonal antibody, Unconjugated

Product Overview

• Article Name: PAG Rabbit monoclonal antibody, Unconjugated
• Biozol Catalog Number: BWT-BS41309
• Supplier Catalog Number: BS41309
• Alternative Catalog Number: BWT-BS41309-50UL,BWT-BS41309-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: FC, IHC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human PAG
• Conjugation: Unconjugated
• Alternative Names: CBP, Csk binding protein, PAG, PAG1,

Product Description

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.

Product Properties

• Molecular Weight: 80kDa
• UniProt: Q9NWQ8
• Purity: Affinity-chromatography
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application Notes

• Application Dilute: WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:100
• Application Notes: PAG Antibody detects endogenous levels of total PAG