Caspase 5 p10 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Caspase 5 p10 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS5645
• Hersteller Artikelnummer: BS5645
• Alternativnummer: BWT-BS5645-50UL,BWT-BS5645-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 341-386 of Human Caspase-5.
• Konjugation: Unconjugated
• Alternative Synonym: Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, Caspase-5 subunit p10, CASP5, ICH3, Caspase5

Produktbeschreibung

Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating the caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. The human caspase 5 gene maps to chromosome 11q22.2-q22.3 and encodes a protein whose expression is barely detectable in most tissues except brain, with highest expression levels being found in lung, liver and skeletal muscle.

Produkteigenschaften

• Molekulargewicht: ~ 10, 48 kDa
• UniProt: P51878
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500~1:1000
• Anwendungsbeschreibung: Caspase 5 p10 polyclonal antibody recognizes endogenous levels of total caspase-5 protein and the p10 subunit of mature caspase-5.