Cyclin H (Phospho-T315) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS64522
Hersteller Artikelnummer:
BS64522
Alternativnummer:
BWT-BS64522-50UL,BWT-BS64522-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Synthetic phosphopeptide derived from human Cyclin H around the phosphorylation site of Threonine 315.
Konjugation:
Unconjugated
Alternative Synonym:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB:1:500~1:1000 IHC:1:50~1:200
Anwendungsbeschreibung:
Cyclin H (Phospho-T315) polyclonal antibody detects endogenous levels of Cyclin H protein only when phosphorylated at Thr315.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
