Cyclin H (Phospho-T315) polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS64522
Supplier Catalog Number:
BS64522
Alternative Catalog Number:
BWT-BS64522-50UL,BWT-BS64522-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic phosphopeptide derived from human Cyclin H around the phosphorylation site of Threonine 315.
Conjugation:
Unconjugated
Alternative Names:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB:1:500~1:1000 IHC:1:50~1:200
Application Notes:
Cyclin H (Phospho-T315) polyclonal antibody detects endogenous levels of Cyclin H protein only when phosphorylated at Thr315.
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