CD86 Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: CD86 Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS65646
• Hersteller Artikelnummer: BS65646
• Alternativnummer: BWT-BS65646-50UL,BWT-BS65646-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-247 of human CD86 (NP_787058.4).
• Konjugation: Unconjugated
• Alternative Synonym: CD28LG2, FUN1, LAB72, Activation B7 2 antigen, Activation B7-2 antigen 3, CD86_HUMAN, Activation B7-2 antigen, Activation B72 antigen, B lymphocyte activation antigen B7 2, B lymphocyte activation antigen B72, B-lymphocyte activation antigen B7-2 2, B-lymphocyte activation antigen B7-2, B7 2, B7 2 antigen, B7, B7-2, B7.2, B70, B72 antigen, BU63, CD 86, CD28 antigen ligand 2 2, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2, CD86 antigen, CD86 molecule, CLS1, CTLA 4 counter receptor B7 2, CTLA 4 counter receptor B7.2, CTLA-4 counter-receptor B7.2 2, 3, CTLA4 counter receptor B72, Early T-cell costimulatory molecule 1, ETC-1, FUN 1, LAB72, Ly-58, Ly58, MB7, MB7-2, Membrane glycoprotein, MGC34413, T lymphocyte activation antigen CD86, T-lymphocyte activation antigen CD86, TS/A-2

Produktbeschreibung

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

Produkteigenschaften

• Molekulargewicht: ~ 65-70 kDa
• UniProt: P42081
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:100-1:500 IF/ICC: 1:50-1:200 IP: 1:50-1:200
• Anwendungsbeschreibung: CD86 Polyclonal Antibody detects endogenous levels of CD86 protein.